WARFARIN - Coumadin -> Indication: DVT (ORAL) Class: Anticoagulant Mode of Action: Inhibits Vitamin K dependent clotting factors Use: Prevent/Treat blood clots Side Effects: Bleeding (Bleeding Gums Blood nose) Bruising Skin Necrosis (Rare) Food/Fluid: up to patient choice NI: Assess Patient Vital Signs especially Bp HR & RR. (Due risk bleeding and response medication) Tests PT (Prothrombin Time) INR (International Normalized Ratio) C: Pregnancy Risk for fetus develop Active P: dehydration affect thickness / Liver Disease Warfarin metabolism occurs in the liver D: Antibiotics (Ciproflaxacin) NSAIDs eg. ibuprofen